Eslicarbazepine acetate

🧮 Dose calculator

Epilepsy (complex partial / absence seizures) · Regimen source: FDA Aptiom · 2.2

• • Start 400 mg (or 800 mg if needed); increase weekly by 400–600 mg. Not with oxcarbazepine. FDA Aptiom · 2.2FDA Aptiom · 2.3

Enter age (weight is optional for this regimen).

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Aptiom · 8.1

  “Risk Summary Limited available data with APTIOM use in pregnant women are insufficient to inform a drug-associated risk of adverse developmental outcomes.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Aptiom · 8.2

  “Eslicarbazepine is present in human milk.”

• 👶 ChildrenUse with caution

  The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Aptiom · 8.4

  “Safety and effectiveness of APTIOM have been established in the age groups 4 to 17 years.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Aptiom · 8.5

  “Although the pharmacokinetics of eslicarbazepine are not affected by age independently, dose selection should take in consideration the greater frequency of renal impairment and other concomitant medical conditions and drug therapies in the elderly patient.”

• ⚥ Females & males of reproductive potentialUse with caution

  Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Aptiom · 8.3

  “Contraception Use of APTIOM with hormonal contraceptives containing ethinylestradiol or levonorgestrel is associated with lower plasma levels of these hormones.”