Primidone

پریمیدون

⚠ Unverified

🧠 Nervous SystemAntiseizure (deoxybarbiturate)

Market / country: 🇺🇸 USA

Mysoline (US)

🧮 Dose calculator

Epilepsy (complex partial / absence seizures) · Regimen source: FDA Primidone · Dosage and Administration

  • • Start 100–125 mg at bedtime and build over 10 days (day 4: twice, day 7: three times, day 10: 250 mg three times). Usually 750–1000 mg/day; max 500 mg four times daily. Effective serum level 5–12 µg/mL. FDA Primidone · Dosage and Administration

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🛡️ Safety & information

Contraindications

Warnings

  • • Abrupt withdrawal may precipitate status epilepticus; therapeutic efficacy takes several weeks to assess. FDA Primidone · Warnings

Formulations

👥 Special populations

  • 🤰 PregnancyUse with caution

    Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Primidone · Pregnancy

    “To provide information regarding the effects of in utero exposure to primidone, physicians are advised to recommend that pregnant patients taking primidone enroll in the North American Antiepileptic Drug (NAAED) Pregnancy Registry.”
  • 🤱 BreastfeedingUse with caution

    Label: use with caution while breastfeeding; see the label text. FDA Primidone · Nursing Mothers

    “There is evidence in mothers treated with primidone, the drug appears in the milk in substantial quantities.”
  • 👶 ChildrenNo data

    The source for this drug has no section for this group.

  • 👴 Older adultsNo data

    The source for this drug has no section for this group.

  • ⚥ Females & males of reproductive potentialNo data

    The source for this drug has no section for this group.

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