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Lamotrigine
لاموتریژین
🧠 Neurology, headache & migraineAnticonvulsant / mood stabiliser
Market / country: 🇺🇸 USA
Lamictal (US)
🧮 Dose calculator
Bipolar disorder maintenance · Regimen source: FDA Lamotrigine · 2.4FDA Lamotrigine · 2.4, Table 5
⛔ Target 200 mg/day; with valproate 100 mg/day; with carbamazepine/phenytoin/phenobarbital without valproate 400 mg/day. Escalation must follow the label tables exactly (depends on valproate or enzyme inducers) to reduce the risk of fatal rash; Doz does not calculate these tables. FDA Lamotrigine · 2.4FDA Lamotrigine · 2.4, Table 5
🛡️ Safety & information
Contraindications
- ⛔ Hypersensitivity (rash, angioedema, urticaria, mucosal ulceration) to lamotrigine. FDA Lamotrigine · 4
- ⚠️ Boxed warning: serious rash (SJS/TEN); 0.3–0.8% in children. Higher risk with valproate, high starting dose or rapid escalation. FDA Lamotrigine · Boxed Warning
Formulations
- 25 mg tablet — orally disintegrating tablet 🇺🇸 USA FDA Lamotrigine · 3
- 50 mg tablet — orally disintegrating tablet 🇺🇸 USA FDA Lamotrigine · 3
- 100 mg tablet — orally disintegrating tablet 🇺🇸 USA FDA Lamotrigine · 3
- 200 mg tablet — orally disintegrating tablet 🇺🇸 USA FDA Lamotrigine · 3
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Lamotrigine · 3FDA Lamotrigine · 2.4FDA Lamotrigine · 2.4, Table 5FDA Lamotrigine · 2.2, Tables 1–2FDA Lamotrigine · 4FDA Lamotrigine · Boxed Warning
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Clinical review⚠ Unverified