Epilepsy (complex partial / absence seizures)
Epilepsy (complex partial / absence seizures) · ICD-10: G40.909
Symptoms
- • Focal seizures, with or without loss of awareness
- • Generalized seizures affecting both sides of the brain
- • Absence seizures: brief staring spells
Drugs and regimens
Epilepsy — under 6 y: start 10–20 mg/kg/day
Epilepsy — 6–12 y: start 100 mg twice daily
Epilepsy — adults and >12 y: start 200 mg twice daily
Seizures — children ≤10 y or 30 kg: start 0.01–0.03 mg/kg/day
Seizures — adults: start ≤1.5 mg/day in 3 doses
Complex partial seizures — ≥10 y: start 10–15 mg/kg/day
Partial seizures — ≥12 y: 300 mg three times daily
Partial seizures — 3–11 y: start 10–15 mg/kg/day in 3 doses
Epilepsy — adults and children
Partial seizures — ≥16 y: 500 mg twice daily
Partial seizures — 1–6 months: 7 mg/kg twice daily (target 21)
Partial seizures — 6 months–4 y: 10 mg/kg twice daily (target 25)
Partial seizures — 4–15 y: 10 mg/kg twice daily (target 30)
Partial seizures — adults: start 600 mg/day in two doses
Partial seizures — 4–16 y: start 8–10 mg/kg/day in two doses
Epilepsy — adults: 100 mg three times daily
Epilepsy — children: 5 mg/kg/day in 2 or 3 doses
Partial seizures (adjunct) — ≥17 y: start 150 mg/day
Partial seizures (adjunct) — child ≥30 kg: start 2.5 mg/kg/day
Partial seizures (adjunct) — child <30 kg: start 3.5 mg/kg/day
Epilepsy monotherapy — ≥10 y: target 400 mg/day in two doses
Complex partial seizures — ≥10 y: start 10–15 mg/kg/day
Absence seizures — start 15 mg/kg/day