Zonisamide
زونیسامید
🧠 Nervous SystemAntiepileptic (sulfonamide)
Market / country: 🇺🇸 USA
Zonegran (US)
🧮 Dose calculator
Epilepsy (complex partial / absence seizures) · Regimen source: FDA Zonegran · Dosage and Administration
- • Once or twice daily. 100–600 mg/day effective but no added response above 400; little experience above 600. Swallow capsules whole. FDA Zonegran · Dosage and Administration
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Hypersensitivity to sulfonamides or zonisamide. FDA Zonegran · Contraindications
Warnings
- • Potentially fatal sulfonamide reactions (SJS/TEN, hepatic necrosis, aplastic anaemia); oligohidrosis and hyperthermia in children; metabolic acidosis; kidney stones; suicidal ideation. FDA Zonegran · Warnings
Formulations
- 25 mg capsule — capsule 🇺🇸 USA FDA Zonegran · How Supplied
- 100 mg capsule — capsule 🇺🇸 USA FDA Zonegran · How Supplied
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Zonegran · Precautions/Warnings – Pregnancy
“ZONEGRAN should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.”
- 🤱 BreastfeedingNo data
The source for this drug has no section for this group.
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Zonegran · Pediatric Use:
“The safety and effectiveness of ZONEGRAN in children under age 16 have not been established.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Zonegran · Geriatric Use:
“In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)NDA020789
- DailyMed (FDA label)FDA Zonegran
- MedlinePlus (NIH)Zonisamide
- WHO ATC/DDDN03AX15
- Darooyab (Iran)Zonisamide
🇮🇷 Registered in Iran Darooyab · G-692/Zonisamide
Dosage forms with Iranian generic codes, per Darooyab.
- 03545 · ZONISAMIDE 100MG CAP · کپسول زونیسامید ۱۰۰ میلیگرم
- 09500 · ZONISAMIDE 100MG TAB · قرص زونیسامید ۱۰۰ میلیگرم
- 07684 · ZONISAMIDE 25MG CAP · کپسول زونیسامید ۲۵ میلیگرم
- 07854 · ZONISAMIDE 50MG CAP · کپسول زونیسامید ۵۰ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Zonegran · How SuppliedFDA Zonegran · Dosage and AdministrationFDA Zonegran · ContraindicationsFDA Zonegran · WarningsFDA Zonegran · Precautions/Warnings – PregnancyFDA Zonegran · Pediatric Use:FDA Zonegran · Geriatric Use:FDA Zonegran · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-692/Zonisamide
- Clinical review⚠ Unverified