Perampanel

🧮 Dose calculator

Epilepsy (complex partial / absence seizures) · Regimen source: FDA Fycompa · 2.1

• • With moderate/strong CYP3A4 inducers (carbamazepine, phenytoin, oxcarbazepine) start at 4 mg. Primary generalised tonic-clonic (≥12 y): maintenance 8 mg. FDA Fycompa · 2FDA Fycompa · 2.2

Enter age (weight is optional for this regimen).

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Fycompa · 8.1

  “Risk Summary There are no adequate data on the developmental risk associated with use in pregnant women.”

• 🤱 BreastfeedingNo data

  The source for this drug has no section for this group.

• 👶 ChildrenUse with caution

  The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Fycompa · 8.4

  “Safety and effectiveness of FYCOMPA for the treatment of partial-onset seizures have been established in pediatric patients 4 years of age and older.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Fycompa · 8.5

  “Clinical studies of FYCOMPA did not include sufficient numbers of patients aged 65 and over to determine the safety and efficacy of FYCOMPA in the elderly population.”

• ⚥ Females & males of reproductive potentialUse with caution

  Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Fycompa · 8.3

  “Contraception Use of FYCOMPA may reduce the efficacy of hormonal contraceptives containing levonorgestrel.”