Vigabatrin

🧮 Dose calculator

Infantile spasms (West syndrome) · Regimen source: FDA Vigabatrin · 2.3

• • Increase by 25–50 mg/kg/day every 3 days. FDA Vigabatrin · 2.3

Enter age and weight.

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Vigabatrin · 8.1

  “Risk Summary There are no adequate data on the developmental risk associated with the use of vigabatrin in pregnant women.”

• 🤱 BreastfeedingDangerous / avoid

  Label: breastfeeding not recommended, or choose between the drug and breastfeeding. FDA Vigabatrin · 8.2

  “Because of the potential for serious adverse reactions from vigabatrin in nursing infants, breastfeeding is not recommended.”

• 👶 ChildrenUse with caution

  The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Vigabatrin · 8.4

  “The safety and effectiveness of vigabatrin as adjunctive treatment of refractory complex partial seizures in pediatric patients 2 to 16 years of age have been established and is supported by three double-blind, placebo-controlled studies in patients 3 to 16 years of age, adequate and well-controlled studies in adult …”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Vigabatrin · 8.5

  “Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function.”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.