Lacosamide

🧮 Dose calculator

Epilepsy (complex partial / absence seizures) · Regimen source: FDA Vimpat · 2.1, Table 1

• • Increase weekly by 50 mg twice daily. Adjunctive maintenance 100–200 mg twice daily; adult monotherapy: start 100 mg twice daily, maintain 150–200 mg twice daily. FDA Vimpat · 2.1, Table 1

Enter age and weight.

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Vimpat · 8.1

  “Risk Summary Available data from the North American Antiepileptic Drug (NAAED) pregnancy registry, a prospective cohort study, case reports, and a case series with VIMPAT use in pregnant women are insufficient to identify a drug-associated risk of major birth defects, miscarriage or other adverse maternal or fetal …”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Vimpat · 8.2

  “Risk Summary Data from published literature indicate that lacosamide is present in human milk.”

• 👶 ChildrenUse with caution

  The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Vimpat · 8.4

  “Partial-Onset Seizures Safety and effectiveness of VIMPAT for the treatment of partial-onset seizures have been established in pediatric patients 1 month to less than 17 years of age.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Vimpat · 8.5

  “In elderly patients, dose titration should be performed with caution, usually starting at the lower end of the dosing range, reflecting the greater frequency of decreased hepatic function, decreased renal function, increased cardiac conduction abnormalities, and polypharmacy [see Dosage and Administration (2.1 , 2.4 , …”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.