Tocilizumab

🧮 Dose calculator

Rheumatoid arthritis · Regimen source: FDA Actemra · 2.2

• • Do not start if ANC <2000, platelets <100,000 or ALT/AST >1.5× ULN. FDA Actemra · 2.1

Enter age and weight.

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Actemra · 8.1

  “Risk Summary The available data with ACTEMRA from a pregnancy exposure registry, retrospective cohort study, pharmacovigilance, and published literature are insufficient to draw conclusions about a drug-associated risk of major birth defects, miscarriage, or other adverse maternal or fetal outcomes.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Actemra · 8.2

  “Risk Summary No information is available on the presence of tocilizumab in human milk, the effects of the drug on the breastfed infant, or the effects of the drug on milk production.”

• 👶 ChildrenUse with caution

  The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Actemra · 8.4

  “COVID-19 – Intravenous Use The safety and effectiveness of ACTEMRA have been established for the treatment of pediatric patients aged 2 years and older with COVID-19.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Actemra · 8.5

  “As there is a higher incidence of infections in the elderly population in general, caution should be used when treating the elderly.”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.