Abatacept

🧮 Dose calculator

Rheumatoid arthritis · Regimen source: FDA Orencia · 2

• • 30-minute infusion. Not with JAK inhibitors or biologic DMARDs (e.g. TNF antagonists). FDA Orencia · 2FDA Orencia · 2.1

Enter age and weight.

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Orencia · 8.1

  “Risk Summary The data with ORENCIA use in pregnant women are insufficient to inform on drug-associated risk.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Orencia · 8.2

  “Risk Summary There is no information regarding the presence of abatacept in human milk, the effects on the breastfed infant, or the effects on milk production.”

• 👶 ChildrenUse with caution

  The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Orencia · 8.4

  “Polyarticular Juvenile Idiopathic Arthritis The safety and effectiveness of ORENCIA for reducing signs and symptoms in patients 2 years of age and older with moderately to severely active polyarticular juvenile idiopathic arthritis (pJIA) have been established (ORENCIA may be used as monotherapy or concomitantly with …”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Orencia · 8.5

  “Because there is a higher incidence of infections and malignancies in the geriatric population in general, caution should be used when treating geriatric patients.”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.