Baricitinib
باریسیتینیب
🎗️ Antineoplastic And Immunomodulating AgentsJAK inhibitor
Market / country: 🇺🇸 USA
Olumiant (US)
🧮 Dose calculator
Rheumatoid arthritis · Regimen source: FDA Olumiant · 2.2
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Warnings
- • Boxed warning (JAK inhibitors): serious infections, mortality, malignancy, major adverse cardiovascular events and thrombosis. TB test before starting. FDA Olumiant · Boxed Warning
Formulations
- 1 mg tablet — tablet 🇺🇸 USA FDA Olumiant · 3
- 2 mg tablet — tablet 🇺🇸 USA FDA Olumiant · 3
- 4 mg tablet — tablet 🇺🇸 USA FDA Olumiant · 3
👥 Special populations
- 🤰 PregnancyDangerous / avoid
Label: can cause fetal harm. Dangerous in pregnancy. FDA Olumiant · 8.1
“Risk Summary Based on the findings from animal reproduction studies, OLUMIANT may cause fetal harm during pregnancy.”
- 🤱 BreastfeedingDangerous / avoid
Label: breastfeeding not recommended, or choose between the drug and breastfeeding. FDA Olumiant · 8.2
“Because of the potential for serious adverse reactions in nursing infants advise women not to breastfeed during treatment with OLUMIANT and for 4 days after the last dose (approximately 5 to 6 elimination half-lives).”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Olumiant · 8.4
“The safety and effectiveness of OLUMIANT for the treatment of severe alopecia areata have been established in pediatric patients 12 years of age and older.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Olumiant · 8.5
“Because geriatric patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function [see Dosage and Administration ( 2.6 )] .”
- ⚥ Females & males of reproductive potentialUse with caution
Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Olumiant · 8.3
“Contraception Based on animal studies, OLUMIANT may cause fetal harm when administered during pregnancy [see Use in Specific Populations ( 8.1 )] .”
🔗 Reference links
- FDA (approval record)NDA207924
- DailyMed (FDA label)FDA Olumiant
- MedlinePlus (NIH)Baricitinib
- WHO ATC/DDDL04AF02
- Darooyab (Iran)Baricitinib
🇮🇷 Registered in Iran Darooyab · G-1716/Baricitinib
Dosage forms with Iranian generic codes, per Darooyab.
- 52844 · BARICITINIB 2MG TAB · قرص باریسیتینیب ۲ میلیگرم
- 52845 · BARICITINIB 4MG TAB · قرص باریسیتینیب ۴ میلیگرم
- 52937 · BARICITINIB TABLET ORAL 1 mg · قرص باریسیتینیب ۱ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Olumiant · 3FDA Olumiant · 2.2FDA Olumiant · 2.3FDA Olumiant · 2.4FDA Olumiant · Boxed WarningFDA Olumiant · SPL approval / marketing categoryFDA Olumiant · 8.1FDA Olumiant · 8.2FDA Olumiant · 8.4FDA Olumiant · 8.5FDA Olumiant · 8.3
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-1716/Baricitinib
- Clinical review⚠ Unverified