Baricitinib

باریسیتینیب

⚠ Unverified

🎗️ Antineoplastic And Immunomodulating AgentsJAK inhibitor

Market / country: 🇺🇸 USA

Olumiant (US)

🧮 Dose calculator

Rheumatoid arthritis · Regimen source: FDA Olumiant · 2.2

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🛡️ Safety & information

Warnings

  • • Boxed warning (JAK inhibitors): serious infections, mortality, malignancy, major adverse cardiovascular events and thrombosis. TB test before starting. FDA Olumiant · Boxed Warning

Formulations

👥 Special populations

  • 🤰 PregnancyDangerous / avoid

    Label: can cause fetal harm. Dangerous in pregnancy. FDA Olumiant · 8.1

    “Risk Summary Based on the findings from animal reproduction studies, OLUMIANT may cause fetal harm during pregnancy.”
  • 🤱 BreastfeedingDangerous / avoid

    Label: breastfeeding not recommended, or choose between the drug and breastfeeding. FDA Olumiant · 8.2

    “Because of the potential for serious adverse reactions in nursing infants advise women not to breastfeed during treatment with OLUMIANT and for 4 days after the last dose (approximately 5 to 6 elimination half-lives).”
  • 👶 ChildrenUse with caution

    The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Olumiant · 8.4

    “The safety and effectiveness of OLUMIANT for the treatment of severe alopecia areata have been established in pediatric patients 12 years of age and older.”
  • 👴 Older adultsUse with caution

    Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Olumiant · 8.5

    “Because geriatric patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function [see Dosage and Administration ( 2.6 )] .”
  • ⚥ Females & males of reproductive potentialUse with caution

    Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Olumiant · 8.3

    “Contraception Based on animal studies, OLUMIANT may cause fetal harm when administered during pregnancy [see Use in Specific Populations ( 8.1 )] .”

📚 Reference status for this drug

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