Remdesivir
رمدسیویر
🦠 Antiinfectives For Systemic UseViral RNA polymerase inhibitor
Market / country: 🇺🇸 USA
Veklury (US)
🧮 Dose calculator
COVID-19 · Regimen source: FDA Veklury · 2.3
- • Hospitalised without ventilation: 5 days (up to 10 if no improvement); ventilation/ECMO: 10 days. Liver tests and PT before starting. No renal adjustment. FDA Veklury · 2.3FDA Veklury · 2.2FDA Veklury · 2.4
Enter age and weight.
🛡️ Safety & information
Contraindications
- ⛔ History of clinically significant hypersensitivity to remdesivir. FDA Veklury · 4
Warnings
- • Infusion-related and hypersensitivity reactions; transaminase elevations. FDA Veklury · 5
Formulations
- 100 mg vial — powder for injection 🇺🇸 USA FDA Veklury · 3
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Veklury · 8.1
“Risk Summary Available data from a clinical trial (IMPAACT 2032), published reports, the COVID-PR pregnancy exposure registry, and compassionate use of remdesivir in pregnant individuals have not identified a drug-associated risk of major birth defects, miscarriage, or adverse maternal or fetal outcomes following …”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Veklury · 8.2
“Risk Summary A published case report describes the presence of remdesivir and active metabolite GS-441524 in human milk.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Veklury · 8.4
“The safety and effectiveness of VEKLURY for the treatment of COVID-19 have been established in pediatric patients from birth to less than 18 years of age and weighing at least 1.5 kg, who are: Hospitalized, or Not hospitalized and have mild-to-moderate COVID-19, and are at high risk for progression to severe COVID-19, …”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Veklury · 8.5
“In general, appropriate caution should be exercised in the administration of VEKLURY and monitoring of elderly patients, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)NDA214787
- DailyMed (FDA label)FDA Veklury
- MedlinePlus (NIH)Remdesivir Injection
- WHO ATC/DDDJ05AB16
- Darooyab (Iran)Remdesivir
🇮🇷 Registered in Iran Darooyab · G-5408/Remdesivir
Dosage forms with Iranian generic codes, per Darooyab.
- 52707 · REMDESIVIR INJECTION, SOLUTION PARENTERAL 5 mg/1mL 20MILLILITER · محلول تزریقی رمدسیویر ۵ میلیگرم / ۱ میلیلیتر ۲۰ میلیلیتر
- 52689 · REMDESIVIR INJECTION, POWDER, FOR SOLUTION PARENTERAL 100 mg · پودر برای تهیه محلول تزریقی رمدسیویر ۱۰۰ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Veklury · 3FDA Veklury · 2.3FDA Veklury · 2.2FDA Veklury · 2.4FDA Veklury · 2.3, Table 1FDA Veklury · 4FDA Veklury · 5FDA Veklury · SPL approval / marketing categoryFDA Veklury · 8.1FDA Veklury · 8.2FDA Veklury · 8.4FDA Veklury · 8.5
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-5408/Remdesivir
- Clinical review⚠ Unverified