Remifentanil

🧮 Dose calculator

General anaesthesia and premedication (adjunct) · Regimen source: FDA Ultiva · 2.2, Table 1

• • Induction: 0.5–1 mcg/kg/min; initial bolus 1 mcg/kg over 30–60 s. With nitrous oxide 0.4 mcg/kg/min. Over 65: halve the starting dose. Obesity: ideal body weight. Infusion device only; not adequate as sole anaesthetic. FDA Ultiva · 2.2, Table 1FDA Ultiva · 2.6FDA Ultiva · 2.9FDA Ultiva · 2.1
• • Only by personnel trained in anaesthesia, with airway, ventilation and resuscitation equipment at hand. FDA Ultiva · 2.1

Enter age and weight.

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Ultiva · 8.1

  “Risk Summary Use of opioid analgesics for an extended period of time during pregnancy may cause neonatal opioid withdrawal syndrome.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Ultiva · 8.2

  “Because fentanyl analogs are excreted in human milk, caution should be exercised when ULTIVA is administered to a nursing woman.”

• 👶 ChildrenUse with caution

  The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Ultiva · 8.4

  “The efficacy and safety of ULTIVA as an analgesic agent for use in the maintenance of general anesthesia in outpatient and inpatient pediatric surgery have been established in controlled clinical studies in pediatric patients from birth to 12 years [see Clinical Studies (14.4) ] .”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Ultiva · 8.5

  “Titrate the dosage of ULTIVA slowly in geriatric patients and frequently reevaluate the patient for signs of central nervous system and respiratory depression [see Warnings and Precautions (5.2) ] .”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.