Desflurane
دسفلوران
🧠 Nervous SystemHalogenated inhalational anaesthetic
Market / country: 🇺🇸 USA
Suprane (US)
🧮 Dose calculator
General anaesthesia and premedication (adjunct) · Regimen source: FDA Suprane · 2.3FDA Suprane · 2.2FDA Suprane · 2.6FDA Suprane · 4
🛡️ Safety & information
Contraindications
- ⛔ Known or suspected genetic susceptibility to malignant hyperthermia; sensitivity to this or other halogenated anaesthetics; induction in children; history of hepatic dysfunction after anaesthesia. FDA Suprane · 4
Warnings
- • Malignant hyperthermia; perioperative hyperkalaemia (especially myopathies); QT prolongation; hepatic injury; possible neurotoxicity in children under 3 with prolonged anaesthesia. FDA Suprane · 5
Formulations
- Volatile liquid for dedicated vaporizer (100%) — solution 🇺🇸 USA FDA Suprane · 3
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Suprane · 8.1
“Risk Summary There are no adequate and well-controlled studies in pregnant women.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Suprane · 8.2
“Because many drugs are excreted in human milk, caution should be exercised when SUPRANE is administered to a nursing woman.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Suprane · 8.4
“Respiratory Adverse Reactions in Pediatric Patients SUPRANE is indicated for maintenance of anesthesia in infants and children after induction of anesthesia with agents other than SUPRANE, and tracheal intubation.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Suprane · 8.5
“The minimum alveolar concentration (MAC) of SUPRANE decreases with increasing patient age.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)NDA020118
- DailyMed (FDA label)FDA Suprane
- MedlinePlus (NIH)❌ None
- WHO ATC/DDDN01AB07
- Darooyab (Iran)Desflurane
🇮🇷 Not found in Iran list Darooyab · G-2665/Desflurane
Darooyab lists no registered dosage form or brand for this drug. This does not prove it is unavailable.
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Suprane · 3FDA Suprane · 2.3FDA Suprane · 2.2FDA Suprane · 2.6FDA Suprane · 4FDA Suprane · 5FDA Suprane · 8.1FDA Suprane · 8.2FDA Suprane · 8.4FDA Suprane · 8.5FDA Suprane · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-2665/Desflurane
- Clinical review⚠ Unverified