Morphine (oral, immediate-release)

🧮 Dose calculator

Severe pain requiring an opioid · Regimen source: FDA Morphine IR tab · 2.3

• • Lowest effective dose for the shortest time. Tablets not suitable for children under 50 kg. FDA Morphine IR tab · 2.3

Enter age (weight is optional for this regimen).

👥 Special populations

• 🤰 PregnancyDangerous / avoid

  Label: can cause fetal harm. Dangerous in pregnancy. FDA Morphine IR tab · Boxed Warning

  “Neonatal Opioid Withdrawal Syndrome (NOWS) Advise pregnant women using opioids for an extended period of time of the risk of Neonatal Opioid Withdrawal Syndrome, which may be life-threatening if not recognized and treated.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Morphine IR tab · 8.2

  “Risk Summary Morphine is present in breast milk.”

• 👶 ChildrenSafety not established

  Label: not established in children under 50 kg (dose not achievable with tablets). Accidental ingestion by a child can be fatal. FDA Morphine IR tab · 8.4

  “The safety and effectiveness of morphine sulfate tablets have not been established for the management of pediatric patients weighing less than 50 kg”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Morphine IR tab · 8.5

  “In general, use caution when selecting a dose for an elderly patient, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function and of concomitant disease or other drug therapy.”

• ⚥ Females & males of reproductive potentialUse with caution

  Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Morphine IR tab · 8.3

  “Infertility Use of opioids for an extended period of time may cause reduced fertility in females and males of reproductive potential.”