Sevoflurane
سووفلوران
🧠 Nervous SystemHalogenated inhalational anaesthetic
Market / country: 🇺🇸 USA
Ultane (US)
🧮 Dose calculator
General anaesthesia and premedication (adjunct) · Regimen source: FDA Sevoflurane · Dosage and Administration
🛡️ Safety & information
Contraindications
- ⛔ Known or suspected genetic susceptibility to malignant hyperthermia; sensitivity to this or other halogenated anaesthetics. FDA Sevoflurane · Contraindications
Warnings
- • Malignant hyperthermia; perioperative hyperkalaemia (especially myopathies); QT prolongation; hepatic injury; possible neurotoxicity in children under 3 with prolonged anaesthesia. FDA Sevoflurane · Warnings
Formulations
- Volatile liquid for vaporizer (100%) — solution 🇺🇸 USA FDA Sevoflurane · Description
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Sevoflurane · Pregnancy
“Risk Summary There are no adequate and well-controlled studies in pregnant women.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Sevoflurane · Nursing Mothers
“To minimize infant exposure to sevoflurane or its metabolites, a nursing mother may temporarily pump, and discard breast milk produced during the first 24 hours after administration of sevoflurane.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Sevoflurane · Pediatric Use
“Induction and maintenance of general anesthesia with sevoflurane have been established in controlled clinical studies in pediatric patients aged 1 to 18 years (see CLINICAL STUDIES , ADVERSE REACTIONS ).”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Sevoflurane · Geriatric Use
“MAC decreases with increasing age.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)ANDA075895
- DailyMed (FDA label)FDA Sevoflurane
- MedlinePlus (NIH)❌ None
- WHO ATC/DDDN01AB08
- Darooyab (Iran)Sevoflurane
🇮🇷 Registered in Iran Darooyab · G-2926/Sevoflurane
Dosage forms with Iranian generic codes, per Darooyab.
- 02548 · SEVOFLURAN 250ML FOR INHALATION · سووفلوران ۲۵۰ میلیلیتر
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Sevoflurane · DescriptionFDA Sevoflurane · Dosage and AdministrationFDA Sevoflurane · ContraindicationsFDA Sevoflurane · WarningsFDA Sevoflurane · SPL approval / marketing categoryFDA Sevoflurane · PregnancyFDA Sevoflurane · Nursing MothersFDA Sevoflurane · Pediatric UseFDA Sevoflurane · Geriatric Use
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-2926/Sevoflurane
- Clinical review⚠ Unverified