Morphine (injection)

🧮 Dose calculator

Severe pain requiring an opioid · Regimen source: FDA Morphine inj. · 2.2

• • Inject slowly; start low in elderly or debilitated patients. FDA Morphine inj. · 2

Enter age and weight.

👥 Special populations

• 🤰 PregnancyDangerous / avoid

  Label: can cause fetal harm. Dangerous in pregnancy. FDA Morphine inj. · Boxed Warning

  “Neonatal Opioid Withdrawal Syndrome (NOWS) Advise pregnant women using opioids for an extended period of time of the risk of Neonatal Opioid Withdrawal Syndrome, which may be life-threatening if not recognized and treated.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Morphine inj. · 8.2

  “Risk Summary Morphine is present in breast milk.”

• 👶 ChildrenSafety not established

  Label: safety and effectiveness in children have not been established. FDA Morphine inj. · 8.4

  “The safety and effectiveness of morphine sulfate injection in pediatric patients below the age of 18 have not been established.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Morphine inj. · 8.5

  “In general, use caution when selecting a dosage for an elderly patient, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function and of concomitant disease or other drug therapy.”

• ⚥ Females & males of reproductive potentialUse with caution

  Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Morphine inj. · 8.3

  “Infertility Use of opioids for an extended period of time may cause reduced fertility in females and males of reproductive potential.”