Paclitaxel

🧮 Dose calculator

Ovarian cancer · Regimen source: FDA Paclitaxel · Dosage and Administration

• • Or 135 mg/m² over 24 h. Premedicate: dexamethasone 20 mg PO 12 and 6 h before, diphenhydramine 50 mg and cimetidine 300 mg IV 30–60 min before. Non-PVC sets. FDA Paclitaxel · Dosage and Administration
• • Only under an oncologist in an equipped centre. Calculator = label mg/m² × BSA (Mosteller); protocol, cycle interval and adjustment for CBC and renal/hepatic function rest with the oncology team. FDA Paclitaxel · Dosage and Administration

Enter age and weight.

👥 Special populations

• 🤰 PregnancyDangerous / avoid

  Label: can cause fetal harm. Dangerous in pregnancy. FDA Paclitaxel · Pregnancy

  “Paclitaxel injection can cause fetal harm when administered to a pregnant woman.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Paclitaxel · Nursing Mothers

  “Following intravenous administration of carbon 14 labeled paclitaxel to rats on days 9 to 10 postpartum, concentrations of radioactivity in milk were higher than in plasma and declined in parallel with the plasma concentrations.”

• 👶 ChildrenSafety not established

  Label: safety and effectiveness in children have not been established. FDA Paclitaxel · Pediatric Use

  “The safety and effectiveness of paclitaxel injection in pediatric patients have not been established.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Paclitaxel · Geriatric Use

  “Of 2228 patients who received paclitaxel in 8 clinical studies evaluating its safety and effectiveness in the treatment of advanced ovarian cancer, breast carcinoma, or NSCLC, and 1570 patients who were randomized to receive paclitaxel in the adjuvant breast cancer study, 649 patients (17%) were 65 years or older and …”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.