Olaparib

🧮 Dose calculator

Ovarian cancer · Regimen source: FDA Lynparza · 2.2

• • Only under an oncologist; continue until progression or unacceptable toxicity. Dose adjustments for toxicity and interactions per label. FDA Lynparza · 2.2
• • Swallow whole. Prostate: with a GnRH analogue or after orchiectomy. Moderate renal impairment: reduce dose. FDA Lynparza · 2.2FDA Lynparza · 2

Enter age (weight is optional for this regimen).

👥 Special populations

• 🤰 PregnancyDangerous / avoid

  Label: can cause fetal harm. Dangerous in pregnancy. FDA Lynparza · 8.1

  “Risk Summary Based on findings in animals and its mechanism of action [see Clinical Pharmacology (12.1) ] , Lynparza can cause fetal harm when administered to a pregnant woman.”

• 🤱 BreastfeedingDangerous / avoid

  Label: breastfeeding not recommended, or choose between the drug and breastfeeding. FDA Lynparza · 8.2

  “Because of the potential for serious adverse reactions in the breastfed infants from Lynparza, advise a lactating woman not to breastfeed during treatment with Lynparza and for one month after receiving the last dose.”

• 👶 ChildrenUse with caution

  The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Lynparza · 8.4

  “Safety and effectiveness of Lynparza have not been established in pediatric patients.”

• 👴 Older adultsNo specific problem stated

  Label: no specific difference or dose adjustment stated for older adults. FDA Lynparza · 8.5

  “No overall differences in the safety or effectiveness of Lynparza were observed between these patients and younger patients.”

• ⚥ Females & males of reproductive potentialUse with caution

  Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Lynparza · 8.3

  “Contraception Females Advise females of reproductive potential to use effective contraception during treatment with Lynparza and for 6 months following the last dose.”