Cisplatin

🧮 Dose calculator

Testicular cancer · Regimen source: FDA Cisplatin · 2.2

• • Only under an oncologist in an equipped centre. Calculator = label mg/m² × BSA (Mosteller); protocol, cycle interval and adjustment for CBC and renal/hepatic function rest with the oncology team. FDA Cisplatin · 2.2

Enter age and weight.

👥 Special populations

• 🤰 PregnancyDangerous / avoid

  Label: can cause fetal harm. Dangerous in pregnancy. FDA Cisplatin · 8.1

  “Risk Summary Based on human data from published literature, cisplatin for injection can cause fetal harm when administered to pregnant women.”

• 🤱 BreastfeedingDangerous / avoid

  Label: breastfeeding not recommended, or choose between the drug and breastfeeding. FDA Cisplatin · 8.2

  “Because of the potential for serious adverse reactions from cisplatin for injection in a breastfed child and because of the potential for tumorigenicity shown for cisplatin for injection, advise lactating women not to breastfeed during treatment with cisplatin for injection.”

• 👶 ChildrenUse with caution

  The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Cisplatin · 8.4

  “Ototoxic effects may be more severe and detrimental in pediatric patients receiving cisplatin for injection, particularly in patients less than 5 years of age.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Cisplatin · 8.5

  “… ptible to nephrotoxicity, myelosuppression, and infectious complications than are younger patients [see Warnings and Precautions ( 5.1 , 5.2 , 5.4 )].”

• ⚥ Females & males of reproductive potentialUse with caution

  Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Cisplatin · 8.3

  “Contraception Females Cisplatin for injection can cause fetal harm when administered to a pregnant woman [see Use in Specific Populations ( 8.1 )] .”