Anastrozole

🧮 Dose calculator

Breast cancer (hormonal therapy) · Regimen source: FDA Anastrozole · 2.1

• • Advanced: until progression. Adjuvant: five years in the ATAC trial. FDA Anastrozole · 2.1

Enter age (weight is optional for this regimen).

👥 Special populations

• 🤰 PregnancyDangerous / avoid

  Label: can cause fetal harm. Dangerous in pregnancy. FDA Anastrozole · 8.1

  “Risk Summary Based on findings from animal studies and its mechanism of action, anastrozole tablets may cause fetal harm when administered to a pregnant woman [see Clinical Pharmacology (12.1) ] .”

• 🤱 BreastfeedingDangerous / avoid

  Label: breastfeeding not recommended, or choose between the drug and breastfeeding. FDA Anastrozole · 8.2

  “… ole in animal studies, or the potential for serious adverse reactions in the breast-fed child from anastrozole tablets, advise lactating women not to breastfeed during treatment with anastrozole tablets and for 2 weeks after the last dose.”

• 👶 ChildrenUse with caution

  The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Anastrozole · 8.4

  “Clinical studies in pediatric patients included a placebo-controlled trial in pubertal boys of adolescent age with gynecomastia and a single-arm trial in girls with McCune-Albright Syndrome and progressive precocious puberty.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Anastrozole · 8.5

  “In studies 0030 and 0027, about 50% of patients were 65 or older.”

• ⚥ Females & males of reproductive potentialUse with caution

  Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Anastrozole · 8.3

  “Contraception Females Based on animal studies, anastrozole tablets can cause fetal harm when administered to a pregnant woman [see Use in Specific Populations (8.1) ] .”