OnabotulinumtoxinA (Botox)

🧮 Dose calculator

Migraine prophylaxis · Regimen source: FDA Botox · 2.5

• • Botox units are not interchangeable with other botulinum products. In any 3 months: adults max 400 Units; children the lesser of 10 Units/kg or 340 Units. FDA Botox · 2.1FDA Botox · 2

Enter age (weight is optional for this regimen).

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Botox · 8.1

  “Risk Summary There are no studies or adequate data from postmarketing surveillance on the developmental risk associated with use of BOTOX in pregnant women.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Botox · 8.2

  “Risk Summary There are no data on the presence of BOTOX in human or animal milk, the effects on the breastfed infant, or the effects on milk production.”

• 👶 ChildrenUse with caution

  Label: established for some indications (spasticity, neurogenic bladder from 5 y); toxin-spread risk is greatest in children treated for spasticity. FDA Botox · 8.4

  “The safety and effectiveness of BOTOX for detrusor overactivity associated with a neurologic condition have been established in pediatric patients 5 years of age and older.”

• 👴 Older adultsNo specific problem stated

  Label: no specific difference or dose adjustment stated for older adults. FDA Botox · 8.5

  “No overall differences in safety were observed between elderly patients and adult patients younger than 65 years of age.”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.