Trospium
تروسپیوم
🚻 Genito Urinary System And Sex HormonesQuaternary-amine antimuscarinic
Market / country: 🇺🇸 USA
Sanctura (US)
🧮 Dose calculator
Overactive bladder · Regimen source: FDA Trospium · 2
- • ≥75 y: may reduce to 20 mg once daily by tolerability. FDA Trospium · 2
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Urinary retention; gastric retention; uncontrolled narrow-angle glaucoma; hypersensitivity. FDA Trospium · 4
Warnings
- • Urinary retention (especially with bladder outlet obstruction); angioedema; decreased GI motility; CNS effects (confusion, somnolence). FDA Trospium · 5
Renal adjustment
- • eGFR < 30: CrCl <30: 20 mg once daily at bedtime. FDA Trospium · 2
Formulations
- 20 mg tablet — tablet 🇺🇸 USA FDA Trospium · 3
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Trospium · 8.1
“Teratogenic Effects Pregnancy Category C: There are no adequate and well-controlled studies of trospium chloride in pregnant women.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Trospium · 8.3
“Trospium chloride (2 mg/kg orally and 50 mcg/kg intravenously) was excreted, to a limited extent (less than 1%), into the milk of lactating rats (primarily as parent compound).”
- 👶 ChildrenSafety not established
Label: safety and effectiveness in children have not been established. FDA Trospium · 8.4
“The safety and effectiveness of trospium chloride in pediatric patients have not been established.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Trospium · 8.5
“Therefore, based upon tolerability, the dose frequency of trospium chloride may be reduced to 20 mg once daily in patients 75 years of age and older.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)ANDA204945
- DailyMed (FDA label)FDA Trospium
- MedlinePlus (NIH)Trospium
- WHO ATC/DDDG04BD09
- Darooyab (Iran)Trospium-Chloride
🇮🇷 Registered in Iran Darooyab · G-932/Trospium-Chloride
Dosage forms with Iranian generic codes, per Darooyab.
- 16102 · TROSPIUM 20MG TAB · قرص تروسپیوم ۲۰ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Trospium · 3FDA Trospium · 2FDA Trospium · 4FDA Trospium · 5FDA Trospium · 8.1FDA Trospium · 8.3FDA Trospium · 8.4FDA Trospium · 8.5FDA Trospium · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-932/Trospium-Chloride
- Clinical review⚠ Unverified