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Tizanidine
تیزانیدین
🧠 Neurology, headache & migraineMuscle relaxant (alpha-2 agonist)
Market / country: 🇺🇸 USA
Zanaflex (US)
🧮 Dose calculator
Spasticity (MS, spinal cord lesions) · Regimen source: FDA Tizanidine · 2.2
- • Increase by 2–4 mg per dose every 1–4 days; max 36 mg/day. Check liver enzymes at baseline and 1 month. Taper by 2–4 mg/day when stopping. FDA Tizanidine · 2FDA Tizanidine · 2.1FDA Tizanidine · 2.5
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ With strong CYP1A2 inhibitors (fluvoxamine, ciprofloxacin); hypersensitivity. FDA Tizanidine · 4
- ⛔ Not established in children. FDA Tizanidine · 8.4
Formulations
- 2 mg tablet (scored) — tablet 🇺🇸 USA FDA Tizanidine · 3
- 4 mg tablet (scored) — tablet 🇺🇸 USA FDA Tizanidine · 3
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Tizanidine · 3FDA Tizanidine · 2.2FDA Tizanidine · 2FDA Tizanidine · 2.1FDA Tizanidine · 2.5FDA Tizanidine · 4FDA Tizanidine · 8.4
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Clinical review⚠ Unverified