Atogepant
آتوجپانت
🧠 Nervous SystemCGRP receptor antagonist (gepant)
Market / country: 🇺🇸 USA
Qulipta (US)
🧮 Dose calculator
Migraine prophylaxis · Regimen source: FDA Qulipta · 2.1
- • Strong CYP3A4 inhibitors: 10 mg; strong CYP3A4 inducers: 60 mg (not recommended in chronic migraine). Other interactions per Table 1. FDA Qulipta · 2.2, Table 1
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ History of hypersensitivity to atogepant (anaphylaxis, dyspnoea). FDA Qulipta · 4
Warnings
- • Hypersensitivity reactions. FDA Qulipta · 5
Renal adjustment
- • eGFR < 30: CrCl <30 or ESRD: episodic 10 mg; chronic not recommended. FDA Qulipta · 2.2
Formulations
- 60 mg tablet — tablet 🇺🇸 USA FDA Qulipta · 3
- 10 mg tablet — tablet 🇺🇸 USA FDA Qulipta · 3
- 30 mg tablet — tablet 🇺🇸 USA FDA Qulipta · 3
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Qulipta · 8.1
“Risk Summary There are no adequate data on the developmental risk associated with the use of QULIPTA in pregnant women.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Qulipta · 8.2
“Risk Summary Data from a lactation study in twelve healthy adult females indicate that atogepant is excreted in breast milk in low amounts.”
- 👶 ChildrenSafety not established
Label: safety and effectiveness in children have not been established. FDA Qulipta · 8.4
“Safety and effectiveness in pediatric patients have not been established.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Qulipta · 8.5
“In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)NDA215206
- DailyMed (FDA label)FDA Qulipta
- MedlinePlus (NIH)Atogepant
- WHO ATC/DDDN02CD07
- Darooyab (Iran)❌ None
🇮🇷 Not found in Iran list Darooyab · search
Darooyab lists no registered dosage form or brand for this drug. This does not prove it is unavailable.
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Qulipta · 3FDA Qulipta · 2.1FDA Qulipta · 2.2, Table 1FDA Qulipta · 4FDA Qulipta · 5FDA Qulipta · 2.2FDA Qulipta · SPL approval / marketing categoryFDA Qulipta · 8.1FDA Qulipta · 8.2FDA Qulipta · 8.4FDA Qulipta · 8.5
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · search
- Clinical review⚠ Unverified