Vericiguat

وریسیگوات

⚠ Unverified

❤️ Cardiovascular SystemSoluble guanylate cyclase stimulator

Market / country: 🇺🇸 USA

Verquvo (US)

🧮 Dose calculator

Heart failure · Regimen source: FDA Verquvo · 2.1

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🛡️ Safety & information

Contraindications

  • ⛔ Concomitant other soluble guanylate cyclase stimulators (e.g. riociguat); pregnancy. FDA Verquvo · 4

Warnings

  • • Boxed warning: embryo-fetal toxicity — exclude pregnancy before starting and use effective contraception until 1 month after stopping. FDA Verquvo · Boxed Warning

Important interactions

Formulations

👥 Special populations

  • 🤰 PregnancyContraindicated

    Label: contraindicated in pregnancy. FDA Verquvo · 4

    “VERQUVO is contraindicated in pregnancy [see Warnings and Precautions (5.1) and Use in Specific Populations (8.1) ].”
  • 🤱 BreastfeedingDangerous / avoid

    Label: breastfeeding not recommended, or choose between the drug and breastfeeding. FDA Verquvo · 8.2

    “Because of the potential for serious adverse reactions in breastfed infants from VERQUVO, advise women not to breastfeed during treatment with VERQUVO.”
  • 👶 ChildrenUse with caution

    The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Verquvo · 8.4

    “Safety and effectiveness of VERQUVO have not been established in pediatric patients.”
  • 👴 Older adultsNo specific problem stated

    Label: no specific difference or dose adjustment stated for older adults. FDA Verquvo · 8.5

    “No dosage adjustment of VERQUVO is required in geriatric patients.”
  • ⚥ Females & males of reproductive potentialUse with caution

    Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Verquvo · 8.3

    “Contraception Females VERQUVO may cause fetal harm when administered to a pregnant woman.”

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