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Spironolactone

اسپیرونولاکتون

⚠ Unverified

❤️ CardiovascularAldosterone antagonist (potassium-sparing diuretic)

Market / country: 🇺🇸 USA

Aldactone (US)

🧮 Dose calculator

Disease / regimen

Heart failure · Regimen source: FDA Spironolactone · 2.2

• If potassium ≤5.0 and eGFR >50. If tolerated up to 50 mg; with hyperkalemia 25 mg every other day. eGFR 30–50: start every other day. FDA Spironolactone · 2.2 FDA Spironolactone · 2

Formulation

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🛡️ Safety & information

Contraindications

⛔ Hyperkalemia; Addison's disease; concomitant eplerenone. FDA Spironolactone · 4

Formulations

25 mg tablet — tablet 🇺🇸 USA FDA Spironolactone · 3
50 mg tablet (scored) — tablet 🇺🇸 USA FDA Spironolactone · 3
100 mg tablet (scored) — tablet 🇺🇸 USA FDA Spironolactone · 3

📚 Reference status for this drug

Shows which sources have references recorded for this drug and which do not.

FDA label (DailyMed)✅ Present
FDA Spironolactone · 3 FDA Spironolactone · 2.2 FDA Spironolactone · 2 FDA Spironolactone · 2.3 FDA Spironolactone · 2.5 FDA Spironolactone · 8.4 FDA Spironolactone · 4
UK SmPC (eMC / MHRA)❌ Not present
Published guideline❌ Not present
Licensed reference (medical school)❌ Not present
Iranian leaflet (IFDA)❌ Not present
Clinical review⚠ Unverified