Finerenone
فینرنون
❤️ Cardiovascular SystemNon-steroidal mineralocorticoid receptor antagonist
Market / country: 🇺🇸 USA
Kerendia (US)
🧮 Dose calculator
Diabetic nephropathy · Regimen source: FDA Kerendia · 2.2, Table 1FDA Kerendia · 2.3
- • Check potassium before starting: do not start if >5.0. Increase to 20 mg after 4 weeks per potassium and eGFR. eGFR <25: initiation not recommended. FDA Kerendia · 2.1FDA Kerendia · 2.3
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Hypersensitivity; concomitant strong CYP3A4 inhibitors; adrenal insufficiency. FDA Kerendia · 4
Warnings
- • Hyperkalaemia — check potassium before starting and periodically. FDA Kerendia · 5
Formulations
- 10 mg tablet — tablet 🇺🇸 USA FDA Kerendia · 3
- 20 mg tablet — tablet 🇺🇸 USA FDA Kerendia · 3
- 40 mg tablet — tablet 🇺🇸 USA FDA Kerendia · 3
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Kerendia · 8.1
“Risk Summary There are no available data on Kerendia use in pregnancy to evaluate for a drug-associated risk of major birth defects, miscarriage, or adverse maternal or fetal outcomes.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Kerendia · 8.2
“Risk Summary There are no data on the presence of finerenone or its metabolite in human milk, the effects on the breastfed infant or the effects of the drug on milk production.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Kerendia · 8.4
“The safety and efficacy of Kerendia have not been established in patients below 18 years of age.”
- 👴 Older adultsNo specific problem stated
Label: no specific difference or dose adjustment stated for older adults. FDA Kerendia · 8.5
“No dose adjustment is required.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)NDA215341
- DailyMed (FDA label)FDA Kerendia
- MedlinePlus (NIH)Finerenone
- WHO ATC/DDDC03DA05
- Darooyab (Iran)Finerenone
🇮🇷 Registered in Iran Darooyab · G-5551/Finerenone
Dosage forms with Iranian generic codes, per Darooyab.
- 53636 · FINERENONE 10 mg TABLET · قرص فینرنون ۱۰ میلیگرم
- 53637 · FINERENONE 20 mg TABLET · قرص فینرنون ۲۰ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Kerendia · 3FDA Kerendia · 2.2, Table 1FDA Kerendia · 2.3FDA Kerendia · 2.1FDA Kerendia · 2.2FDA Kerendia · 4FDA Kerendia · 5FDA Kerendia · SPL approval / marketing categoryFDA Kerendia · 8.1FDA Kerendia · 8.2FDA Kerendia · 8.4FDA Kerendia · 8.5
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-5551/Finerenone
- Clinical review⚠ Unverified