Eplerenone

🧮 Dose calculator

Heart failure · Regimen source: FDA Eplerenone · 2.1

• • Adjust by serum potassium per label Table 1. Check potassium before starting and periodically. FDA Eplerenone · 2.1FDA Eplerenone · 2.3

Enter age (weight is optional for this regimen).

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Eplerenone · 8.1

  “Risk Summary The available data from published case reports on eplerenone use during pregnancy are insufficient to establish a drug-associated risk of major birth defects, miscarriage, adverse maternal or fetal outcomes (see Clinical Considerations ) .”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Eplerenone · 8.2

  “Risk Summary There are no human data available on whether eplerenone is present in human milk, or has effects on breastfed infants or on milk production.”

• 👶 ChildrenUse with caution

  The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Eplerenone · 8.4

  “The safety and effectiveness of eplerenone for treatment of hypertension have not been established in pediatric patients.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Eplerenone · 8.5

  “However, due to age-related decreases in creatinine clearance, the incidence of laboratory-documented hyperkalemia was increased in patients 65 and older [see Warnings and Precautions (5.1) ] .”

• ⚥ Females & males of reproductive potentialUse with caution

  Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Eplerenone · 8.3

  “Infertility Based on animal data, use of eplerenone may compromise male fertility.”