Ivabradine

🧮 Dose calculator

Heart failure · Regimen source: FDA Corlanor · 2.1

• • After 2 weeks adjust to resting HR 50–60: >60 → +2.5 mg up to 7.5 mg twice daily; <50 or bradycardia → −2.5 mg. Start 2.5 mg twice daily with conduction defects. FDA Corlanor · 2.1

Enter age (weight is optional for this regimen).

👥 Special populations

• 🤰 PregnancyDangerous / avoid

  Label: can cause fetal harm. Dangerous in pregnancy. FDA Corlanor · 8.1

  “Risk Summary Based on findings in animals, Corlanor may cause fetal harm when administered to a pregnant woman.”

• 🤱 BreastfeedingDangerous / avoid

  Label: breastfeeding not recommended, or choose between the drug and breastfeeding. FDA Corlanor · 8.2

  “Because of the potential risk to breastfed infants from exposure to Corlanor, breastfeeding is not recommended.”

• 👶 ChildrenUse with caution

  The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Corlanor · 8.4

  “The safety and effectiveness of Corlanor have been established in pediatric patients (age 6 months to less than 18 years old) and are supported by pharmacokinetic and pharmacodynamic trials and evidence from adequate and well-controlled trials of Corlanor in adult patients.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Corlanor · 8.5

  “No pharmacokinetic differences have been observed in elderly (≥ 65 years) or very elderly (≥ 75 years) patients compared to the overall population.”

• ⚥ Females & males of reproductive potentialUse with caution

  Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Corlanor · 8.3

  “Contraception Females Corlanor may cause fetal harm, based on animal data.”