Leucovorin (folinic acid)

لکوورین (فولینیک اسید)

⚠ Unverified

🧪 VariousFolate analogue (rescue agent)

Market / country: 🇺🇸 USA

Leucovorin (US)

🧮 Dose calculator

Rescue after high-dose methotrexate and antifolate overdose · Regimen source: FDA Leucovorin inj · Dosage and Administration

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🛡️ Safety & information

Contraindications

Warnings

  • • Fatal if given intrathecally; give as soon as possible after antifolate overdose; enhances fluorouracil toxicity (especially elderly). FDA Leucovorin inj · Warnings

Formulations

👥 Special populations

  • 🤰 PregnancyUse with caution

    Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Leucovorin inj · Pregnancy

    “Teratogenic Effects Pregnancy Category C Adequate animal reproduction studies have not been conducted with leucovorin.”
  • 🤱 BreastfeedingUse with caution

    Label: use with caution while breastfeeding; see the label text. FDA Leucovorin inj · Nursing Mothers

    “Because many drugs are excreted in human milk, caution should be exercised when leucovorin is administered to a nursing mother.”
  • 👶 ChildrenUse with caution

    The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Leucovorin inj · Pediatric Use

    “See PRECAUTIONS, Drug Interactions .”
  • 👴 Older adultsUse with caution

    Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Leucovorin inj · Geriatric Use

    “Because elder patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function.”
  • ⚥ Females & males of reproductive potentialNo data

    The source for this drug has no section for this group.

📚 Reference status for this drug

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