Carboplatin
کربوپلاتین
🎗️ Antineoplastic And Immunomodulating AgentsPlatinum compound
Market / country: 🇺🇸 USA
Paraplatin (US)
🧮 Dose calculator
Ovarian cancer · Regimen source: FDA Carboplatin · Dosage and Administration
- • Alternative: formula dosing (Calvert: AUC × [GFR + 25]). Do not repeat until neutrophils ≥2,000 and platelets ≥100,000. FDA Carboplatin · Dosage and Administration
- • Only under an oncologist in an equipped centre. Calculator = label mg/m² × BSA (Mosteller); protocol, cycle interval and adjustment for CBC and renal/hepatic function rest with the oncology team. FDA Carboplatin · Dosage and Administration
Enter age and weight.
🛡️ Safety & information
Contraindications
- ⛔ History of severe allergy to cisplatin or other platinum compounds; severe bone-marrow depression or significant bleeding. FDA Carboplatin · Contraindications
Warnings
- • Boxed warning: bone-marrow suppression (infection, bleeding), vomiting, anaphylactic-like reactions within minutes. FDA Carboplatin · Warnings
Formulations
- 10 mg/mL (50/150/450/600 mg) — injection 🇺🇸 USA FDA Carboplatin · How Supplied
👥 Special populations
- 🤰 PregnancyDangerous / avoid
Label: can cause fetal harm. Dangerous in pregnancy. FDA Carboplatin · Pregnancy
“Pregnancy Category D See WARNINGS.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Carboplatin · Nursing Mothers
“Because there is a possibility of toxicity in nursing infants secondary to carboplatin treatment of the mother, it is recommended that breast-feeding be discontinued if the mother is treated with carboplatin injection.”
- 👶 ChildrenSafety not established
Label: safety and effectiveness in children have not been established. FDA Carboplatin · Pediatric Use
“Safety and effectiveness in pediatric patients have not been established (see WARNINGS : "audiologic toxicity").”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Carboplatin · Geriatric Use
“Of the 789 patients in initial treatment combination therapy studies (NCIC and SWOG), 395 patients were treated with carboplatin in combination with cyclophosphamide.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)ANDA077861
- DailyMed (FDA label)FDA Carboplatin
- MedlinePlus (NIH)Carboplatin Injection
- WHO ATC/DDDL01XA02
- Darooyab (Iran)Carboplatin
🇮🇷 Registered in Iran Darooyab · G-962/Carboplatin
Dosage forms with Iranian generic codes, per Darooyab.
- 00214 · CARBOPLATIN 150MG VIAL · ویال کربوپلاتین ۱۵۰ میلیگرم
- 02376 · CARBOPLATIN 150MG/15ML AMP · آمپول کربوپلاتین ۱۵۰ میلیگرم / ۱۵ میلیلیتر
- 13830 · CARBOPLATIN 450MG/45ML VIAL · ویال کربوپلاتین ۴۵۰ میلیگرم / ۴۵ میلیلیتر
- 13458 · CARBOPLATIN 50MG AMP · آمپول کربوپلاتین ۵۰ میلیگرم
- 00215 · CARBOPLATIN 50MG VIAL · ویال کربوپلاتین ۵۰ میلیگرم
- 02375 · CARBOPLATIN 50MG/5ML VIAL · ویال کربوپلاتین ۵۰ میلیگرم / ۵ میلیلیتر
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Carboplatin · How SuppliedFDA Carboplatin · Dosage and AdministrationFDA Carboplatin · ContraindicationsFDA Carboplatin · WarningsFDA Carboplatin · SPL approval / marketing categoryFDA Carboplatin · PregnancyFDA Carboplatin · Nursing MothersFDA Carboplatin · Pediatric UseFDA Carboplatin · Geriatric Use
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-962/Carboplatin
- Clinical review⚠ Unverified