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Valproic acid (oral solution)
والپروئیک اسید (شربت)
🧠 Neurology, headache & migraineAnticonvulsant
Market / country: 🇺🇸 USA
Depakene (US)
🧮 Dose calculator
Epilepsy (complex partial / absence seizures) · Regimen source: FDA Valproic acid sol. · 2.1
- • Increase by 5–10 mg/kg/week; usual response below 60 mg/kg/day; levels 50–100 mcg/mL. Divide if >250 mg/day. FDA Valproic acid sol. · 2.1
Enter age and weight.
🛡️ Safety & information
Contraindications
- ⛔ Under 2 years: considerably higher risk of fatal hepatotoxicity. FDA Valproic acid sol. · 8.4
- ⛔ Hepatic disease or significant dysfunction; POLG mitochondrial disorders; hypersensitivity; urea-cycle disorders; for migraine prophylaxis: pregnancy or no effective contraception. FDA Valproic acid sol. · 4
- ⚠️ Boxed warning: hepatotoxicity, teratogenicity, pancreatitis. FDA Valproic acid sol. · Boxed Warning
Formulations
- 250 mg/5 mL oral solution — solution 🇺🇸 USA FDA Valproic acid sol. · 3
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Valproic acid sol. · 3FDA Valproic acid sol. · 2.1FDA Valproic acid sol. · 2FDA Valproic acid sol. · 8.4FDA Valproic acid sol. · 4FDA Valproic acid sol. · Boxed Warning
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Clinical review⚠ Unverified