Pramlintide

🧮 Dose calculator

Type 2 diabetes mellitus · Regimen source: FDA Symlin · 2.2

• • On initiation reduce mealtime insulin by 50%. Only before major meals (≥250 kcal or ≥30 g carbohydrate), abdomen or thigh, separate from insulin. At least 3 days between titration steps. FDA Symlin · 2.1FDA Symlin · 2.4

Enter age (weight is optional for this regimen).

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Symlin · 8.1

  “Risk Summary Available data from a small number of reports in the manufacturer’s safety database on SYMLIN use in pregnant women are not sufficient to determine a drug-associated risk for major birth defects, miscarriage, or other adverse maternal or fetal outcomes.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Symlin · 8.2

  “Risk Summary There is no data on the presence of pramlintide in human milk, the effects on the breastfed infant, or the effects on milk production.”

• 👶 ChildrenSafety not established

  Label: safety and effectiveness in children have not been established. FDA Symlin · 8.4

  “Safety and effectiveness of SYMLIN in pediatric patients have not been established.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Symlin · 8.5

  “SYMLIN has been studied in patients ranging in age from 15 to 84 years of age, including 769 patients ≥65 to 75 years of age and 87 patients ≥75 years of age.”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.