Semaglutide (weekly injection)
سماگلوتاید (تزریقی هفتگی)
🍽️ Alimentary Tract And MetabolismGLP-1 receptor agonist
Market / country: 🇺🇸 USA
Ozempic (US)
🧮 Dose calculator
Type 2 diabetes mellitus · Regimen source: FDA Ozempic · 2.2FDA Ozempic · 2.1
🛡️ Safety & information
Contraindications
- ⛔ Personal or family history of medullary thyroid carcinoma or MEN 2; serious hypersensitivity. FDA Ozempic · 4
Warnings
- • Boxed warning: thyroid C-cell tumours in rodents; contraindicated with MTC or MEN 2 history. FDA Ozempic · Boxed Warning
Formulations
- Pen 0.25/0.5 mg, 1 mg or 2 mg per dose (0.68, 1.34 or 2.68 mg/mL) — injection 🇺🇸 USA FDA Ozempic · 3
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Ozempic · 8.1
“Risk Summary There are limited data with semaglutide use in pregnant women to inform a drug-associated risk for adverse developmental outcomes.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Ozempic · 8.2
“Risk Summary There are no data on the presence of semaglutide in human milk, the effects on the breastfed infant, or the effects on milk production.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Ozempic · 8.4
“Safety and efficacy of OZEMPIC have not been established in pediatric patients.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Ozempic · 8.5
“In the pool of placebo- and active-controlled glycemic control trials, 744 (23.6%) OZEMPIC-treated patients were 65 years of age and over and 102 OZEMPIC-treated patients (3.2%) patients were 75 years of age and over.”
- ⚥ Females & males of reproductive potentialUse with caution
Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Ozempic · 8.3
“Discontinue OZEMPIC in women at least 2 months before a planned pregnancy due to the long washout period for semaglutide [see Use in Specific Populations ( 8.1 )] .”
🔗 Reference links
- FDA (approval record)NDA209637
- DailyMed (FDA label)FDA Ozempic
- MedlinePlus (NIH)SemaglutideSemaglutide Injection
- WHO ATC/DDDA10BJ06
- Darooyab (Iran)Semaglutide
🇮🇷 Registered in Iran Darooyab · G-5532/Semaglutide
Dosage forms with Iranian generic codes, per Darooyab.
- 53482 · SEMAGLUTIDE INJECTION, SOLUTION PARENTERAL 4 mg/3 mL · محلول تزریقی سماگلوتاید ۴ میلیگرم / ۳ میلیلیتر
- 53491 · SEMAGLUTIDE INJECTION, SOLUTION PARENTERAL 8 mg/3 mL · محلول تزریقی سماگلوتاید ۸ میلیگرم / ۳ میلیلیتر
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Ozempic · 3FDA Ozempic · 2.2FDA Ozempic · 2.1FDA Ozempic · 4FDA Ozempic · Boxed WarningFDA Ozempic · 8.1FDA Ozempic · 8.2FDA Ozempic · 8.4FDA Ozempic · 8.5FDA Ozempic · 8.3FDA Ozempic · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-5532/Semaglutide
- Clinical review⚠ Unverified