Linagliptin
لیناگلیپتین
🍽️ Alimentary Tract And MetabolismDPP-4 inhibitor
Market / country: 🇺🇸 USA
Tradjenta (US) · Trajenta (GB)
🧮 Dose calculator
Type 2 diabetes mellitus · Regimen source: FDA Tradjenta · 2.1
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Hypersensitivity to linagliptin (anaphylaxis, angioedema…). FDA Tradjenta · 4
Warnings
- • Pancreatitis; bullous pemphigoid; severe joint pain. FDA Tradjenta · 5
Formulations
- 5 mg tablet — tablet 🇺🇸 USA FDA Tradjenta · 3
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Tradjenta · 8.1
“Risk Summary The limited data with TRADJENTA use in pregnant women are not sufficient to inform of drug-associated risk for major birth defects and miscarriage.”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Tradjenta · 8.2
“Risk Summary There is no information regarding the presence of linagliptin in human milk, the effects on the breastfed infant, or the effects on milk production.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Tradjenta · 8.4
“The safety and effectiveness of TRADJENTA have not been established in pediatric patients.”
- 👴 Older adultsNo specific problem stated
Label: no specific difference or dose adjustment stated for older adults. FDA Tradjenta · 8.5
“In these linagliptin studies, no overall differences in safety or effectiveness of linagliptin were observed between geriatric patients and younger adult patients.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)NDA201280
- DailyMed (FDA label)FDA Tradjenta
- MedlinePlus (NIH)Linagliptin
- WHO ATC/DDDA10BH05
- Darooyab (Iran)Linagliptin
🇮🇷 Registered in Iran Darooyab · G-3682/Linagliptin
Dosage forms with Iranian generic codes, per Darooyab.
- 51883 · LINAGLIPTIN 5 mg TABLET · قرص لیناگلیپتین ۵ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Tradjenta · 3FDA Tradjenta · 2.1FDA Tradjenta · 4FDA Tradjenta · 5FDA Tradjenta · 8.1FDA Tradjenta · 8.2FDA Tradjenta · 8.4FDA Tradjenta · 8.5FDA Tradjenta · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-3682/Linagliptin
- Clinical review⚠ Unverified