⚠️ Serious warning: Nothing on this website is approved by any physician. Doz is only a tool to help physicians and to search drugs easily. Taking medicines without medical supervision can be fatal.
Metformin
متفورمین
🧪 Endocrine & metabolismBiguanide
Market / country: 🇺🇸 USA
Glucophage (US)
🧮 Dose calculator
Type 2 diabetes mellitus · Regimen source: FDA Metformin · 2.2FDA Metformin · 8.4
- • With meals; increase by 500 mg weekly per glycemic control and tolerability, max 2000 mg/day in two doses. FDA Metformin · 2.2
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Severe renal impairment (eGFR <30); metabolic acidosis incl. DKA; hypersensitivity. FDA Metformin · 4
- ⛔ Not established under 10 years. FDA Metformin · 8.4
Warnings
- • Boxed warning: lactic acidosis (can be fatal). FDA Metformin · WARNING: LACTIC ACIDOSIS
Renal adjustment
- • eGFR < 45: Initiation not recommended at eGFR 30–45; contraindicated below 30. FDA Metformin · 2.3
- • eGFR < 30: eGFR <30: contraindicated. FDA Metformin · 2.3
Formulations
- 500 mg tablet — tablet 🇺🇸 USA FDA Metformin · 3
- 850 mg tablet — tablet 🇺🇸 USA FDA Metformin · 3
- 1000 mg tablet — tablet 🇺🇸 USA FDA Metformin · 3
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Metformin · 3FDA Metformin · 2.2FDA Metformin · 8.4FDA Metformin · 2.1FDA Metformin · 4FDA Metformin · WARNING: LACTIC ACIDOSISFDA Metformin · 2.3
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Clinical review⚠ Unverified