Palonosetron

پالونوسترون

⚠ Unverified

🍽️ Alimentary Tract And MetabolismLong-acting 5-HT3 antagonist

Market / country: 🇺🇸 USA

Aloxi (US)

🧮 Dose calculator

Chemotherapy-induced nausea and vomiting · Regimen source: FDA Palonosetron · 2.1, Table 1

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🛡️ Safety & information

Contraindications

Warnings

  • • Hypersensitivity (including in those allergic to other 5-HT3 antagonists); serotonin syndrome. FDA Palonosetron · 5

Formulations

👥 Special populations

  • 🤰 PregnancyUse with caution

    Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Palonosetron · 8.1

    “Risk Summary There are no available data on palonosetron HCl use in pregnant women to inform a drug-associated risk.”
  • 🤱 BreastfeedingUse with caution

    Label: use with caution while breastfeeding; see the label text. FDA Palonosetron · 8.2

    “Risk Summary There are no data on the presence of palonosetron in human milk, the effects of palonosetron on the breastfed infant, or the effects of palonosetron on milk production.”
  • 👶 ChildrenUse with caution

    The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Palonosetron · 8.4

    “Chemotherapy-Induced Nausea and Vomiting Safety and effectiveness of palonosetron hydrochloride injection have been established in pediatric patients aged 1 month to less than 17 years for the prevention of acute nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy, …”
  • 👴 Older adultsNo specific problem stated

    Label: no specific difference or dose adjustment stated for older adults. FDA Palonosetron · 8.5

    “No dose adjustment is required for geriatric patients.”
  • ⚥ Females & males of reproductive potentialNo data

    The source for this drug has no section for this group.

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