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Metoclopramide
متوکلوپرامید
🩺 GastrointestinalDopamine antagonist; prokinetic
Market / country: 🇬🇧 UK
Reglan (US) · Maxolon (GB)
🧮 Dose calculator
Chemotherapy-induced nausea and vomiting · Regimen source: UK SmPC Metoclopramide · 4.2
- • At least 6 h between doses, even after vomiting. Maximum 5 days. In children licensed only for this use. UK SmPC Metoclopramide · 4.2UK SmPC Metoclopramide · 4.4
Enter age and weight.
🛡️ Safety & information
Contraindications
- ⛔ Children under 1 year (risk of extrapyramidal disorders). UK SmPC Metoclopramide · 4.3
- ⛔ GI haemorrhage, obstruction or perforation; history of tardive dyskinesia; epilepsy; Parkinson's disease; phaeochromocytoma; with levodopa/dopamine agonists; history of methaemoglobinaemia. UK SmPC Metoclopramide · 4.3
Warnings
- • Extrapyramidal disorders, particularly in children and young adults, even after a single dose; stop immediately if they occur. UK SmPC Metoclopramide · 4.4
- • Tardive dyskinesia with prolonged use; do not exceed 3 months. Neuroleptic malignant syndrome. UK SmPC Metoclopramide · 4.4
Renal adjustment
- • eGFR < 60: CrCl 15–60: reduce dose 50%; ≤15: reduce daily dose 75%. UK SmPC Metoclopramide · 4.2
Formulations
- 5 mg / 5 mL oral solution — solution 🇬🇧 UK UK SmPC Metoclopramide · 1
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)❌ Not present
- UK SmPC (eMC / MHRA)✅ PresentUK SmPC Metoclopramide · 1UK SmPC Metoclopramide · 4.2UK SmPC Metoclopramide · 4.4UK SmPC Metoclopramide · 4.3
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Clinical review⚠ Unverified