Granisetron
گرانیسترون
🍽️ Alimentary Tract And Metabolism5-HT3 antagonist (antiemetic)
Market / country: 🇺🇸 USA
Kytril (US)
🧮 Dose calculator
Chemotherapy-induced nausea and vomiting · Regimen source: FDA Granisetron tab · Dosage and Administration
- • Up to 1 h before chemotherapy. Alternative: 1 mg up to 1 h before and a second 1 mg 12 h later. FDA Granisetron tab · Dosage and Administration
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Hypersensitivity to granisetron or its components. FDA Granisetron tab · Contraindications
Warnings
- • Serotonin syndrome with serotonergic drugs. FDA Granisetron tab · Warnings
Formulations
- 1 mg tablet — tablet 🇺🇸 USA FDA Granisetron tab · How Supplied
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Granisetron tab · Pregnancy
“Teratogenic Effects Pregnancy Category B Reproduction studies have been performed in pregnant rats at oral doses up to 125 mg/kg/day (750 mg/m 2 /day, 507 times the recommended human dose based on body surface area) and pregnant rabbits at oral doses up to 32 mg/kg/day (378 mg/m 2 /day, 255 times the recommended human …”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Granisetron tab · Nursing Mothers
“Because many drugs are excreted in human milk, caution should be exercised when granisetron hydrochloride is administered to a nursing woman.”
- 👶 ChildrenSafety not established
Label: safety and effectiveness in children have not been established. FDA Granisetron tab · Pediatric Use
“Safety and effectiveness in pediatric patients have not been established.”
- 👴 Older adultsUse with caution
Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Granisetron tab · Geriatric Use
“During clinical trials, 325 patients 65 years of age or older received granisetron hydrochloride tablets; 298 were 65 to 74 years of age, and 27 were 75 years of age or older.”
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)ANDA078969
- DailyMed (FDA label)FDA Granisetron tab
- MedlinePlus (NIH)GranisetronGranisetron Injection
- WHO ATC/DDDA04AA02
- Darooyab (Iran)Granisetron
🇮🇷 Registered in Iran Darooyab · G-2590/Granisetron
Dosage forms with Iranian generic codes, per Darooyab.
- 05170 · GRANISETRON 1MG/1ML AMP · آمپول گرانیسترون ۱ میلیگرم / ۱ میلیلیتر
- 08870 · GRANISETRON 3MG/3ML AMP · آمپول گرانیسترون ۳ میلیگرم / ۳ میلیلیتر
- 00609 · GRANISETRON HCL 1MG TAB · قرص گرانیسترون هیدروکلراید ۱ میلیگرم
- 00610 · GRANISETRON HCL 3MG/3ML VIAL · ویال گرانیسترون هیدروکلراید ۳ میلیگرم / ۳ میلیلیتر
- 21313 · GRANISETRON PATCH, EXTENDED RELEASE TRANSDERMAL 34.3 mg/52cm2 · پچ پوستی گرانیسترون ۳۴٫۳ میلیگرم / ۵۲ سانتیمتر ۲
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Granisetron tab · How SuppliedFDA Granisetron tab · Dosage and AdministrationFDA Granisetron tab · ContraindicationsFDA Granisetron tab · WarningsFDA Granisetron tab · PregnancyFDA Granisetron tab · Nursing MothersFDA Granisetron tab · Pediatric UseFDA Granisetron tab · Geriatric UseFDA Granisetron tab · SPL approval / marketing category
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-2590/Granisetron
- Clinical review⚠ Unverified