Fosaprepitant

🧮 Dose calculator

Chemotherapy-induced nausea and vomiting · Regimen source: FDA Fosaprepitant · 2.1

• • Finish about 30 min before chemotherapy; with dexamethasone and a 5-HT3 antagonist. Children 6 months–17 y (≥6 kg) per Tables 3 and 4. FDA Fosaprepitant · 2.1FDA Fosaprepitant · 2.2

Enter age (weight is optional for this regimen).

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Fosaprepitant · 8.1

  “Risk Summary There are insufficient data on use of fosaprepitant in pregnant women to inform a drug associated risk.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Fosaprepitant · 8.2

  “Risk Summary Lactation studies have not been conducted to assess the presence of aprepitant in human milk, the effects on the breastfed infant, or the effects on milk production.”

• 👶 ChildrenUse with caution

  The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Fosaprepitant · 8.4

  “The safety and effectiveness of a single dose and a 3-day regimen of fosaprepitant have been established in pediatric patients 6 months to 17 years for the prevention of acute and delayed nausea and vomiting associated with initial and repeat courses of HEC and MEC.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Fosaprepitant · 8.5

  “In general, use caution when dosing elderly patients as they have a greater frequency of decreased hepatic, renal or cardiac function and concomitant disease or other drug therapy [see Clinical Pharmacology (12.3) ].”

• ⚥ Females & males of reproductive potentialUse with caution

  Label has advice on pregnancy testing, contraception or fertility for females and males. FDA Fosaprepitant · 8.3

  “Contraception Upon administration of fosaprepitant, the efficacy of hormonal contraceptives may be reduced.”