Natalizumab

🧮 Dose calculator

Multiple sclerosis (relapsing) · Regimen source: FDA Tysabri · 2.1

• • TOUCH program only; never IV push; use within 48 h of preparation. Observe 1 h after each of the first 12 infusions. FDA Tysabri · 2.1FDA Tysabri · 2

Enter age (weight is optional for this regimen).

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Tysabri · 8.1

  “Risk Summary There are no adequate data on the risk of major birth defects, miscarriage, or other adverse maternal outcomes associated with the use of TYSABRI in pregnant women.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Tysabri · 8.2

  “Risk Summary Natalizumab has been detected in human milk.”

• 👶 ChildrenSafety not established

  Label: safety and effectiveness in children have not been established. FDA Tysabri · 8.4

  “Safety and effectiveness in pediatric patients with multiple sclerosis or Crohn's disease below the age of 18 years have not been established.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Tysabri · 8.5

  “Clinical studies of TYSABRI did not include sufficient numbers of patients aged 65 years and over to determine whether they respond differently than younger patients.”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.