Interferon beta-1a (IM)

اینترفرون بتا-۱a (عضلانی)

⚠ Unverified

🎗️ Antineoplastic And Immunomodulating AgentsInterferon

Market / country: 🇺🇸 USA

Avonex (US)

🧮 Dose calculator

Multiple sclerosis (relapsing) · Regimen source: FDA Avonex · 2.1

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🛡️ Safety & information

Contraindications

  • ⛔ Hypersensitivity to natural or recombinant interferon beta. FDA Avonex · 4

Warnings

  • • Depression, suicide and psychosis; hepatic injury; anaphylaxis; injection-site necrosis; heart failure; decreased blood counts; thrombotic microangiopathy; seizures. FDA Avonex · 5

Formulations

  • 30 mcg/0.5 mL prefilled syringe or autoinjector — injection 🇺🇸 USA FDA Avonex · 3

👥 Special populations

  • 🤰 PregnancyUse with caution

    Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Avonex · 8.1

    “Risk Summary Data from a large population-based cohort study, as well as other published studies over several decades, have not identified a drug-associated risk of major birth defects with the use of interferon beta products during early pregnancy.”
  • 🤱 BreastfeedingUse with caution

    Label: use with caution while breastfeeding; see the label text. FDA Avonex · 8.2

    “Risk Summary Limited published literature has described the presence of interferon beta-1a products in human milk at low levels.”
  • 👶 ChildrenSafety not established

    Label: safety and effectiveness in children have not been established. FDA Avonex · 8.4

    “Safety and effectiveness in pediatric patients have not been established.”
  • 👴 Older adultsUse with caution

    Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Avonex · 8.5

    “Clinical studies of AVONEX did not include sufficient numbers of patients aged 65 and over to determine whether they respond differently than younger patients.”
  • ⚥ Females & males of reproductive potentialNo data

    The source for this drug has no section for this group.

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