Vedolizumab

🧮 Dose calculator

Ulcerative colitis · Regimen source: FDA Entyvio · 2

• • Infuse over about 30 min. After two IV doses, may switch to 108 mg SC every 2 weeks. Stop if no benefit by week 14. FDA Entyvio · 2

Enter age (weight is optional for this regimen).

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Entyvio · 8.1

  “Risk Summary Available data from the Organization of Teratology Information Specialists (OTIS)/MotherToBaby ENTYVIO Pregnancy Registry, published literature and pharmacovigilance in pregnant women have not reliably identified an ENTYVIO-associated risk of major birth defects, miscarriage or adverse maternal or fetal …”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Entyvio · 8.2

  “Risk Summary Data from a clinical lactation study show the presence of vedolizumab in human milk.”

• 👶 ChildrenSafety not established

  Label: safety and effectiveness in children have not been established. FDA Entyvio · 8.4

  “Safety and effectiveness of ENTYVIO in pediatric patients have not been established.”

• 👴 Older adultsNo specific problem stated

  Label: no specific difference or dose adjustment stated for older adults. FDA Entyvio · 8.5

  “However, no overall differences in safety or effectiveness were observed between these patients and younger adult patients, and other reported clinical experience has not identified differences in responses between the elderly and younger patients.”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.