Meropenem

مروپنم

⚠ Unverified

🦠 Antiinfectives For Systemic UseCarbapenem

Market / country: 🇺🇸 USA

Merrem (US)

🧮 Dose calculator

Skin and skin structure infection · Regimen source: FDA Meropenem · 2.1

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🛡️ Safety & information

Contraindications

  • ⛔ Hypersensitivity to the drug or anaphylaxis with other beta-lactams. FDA Meropenem · 4

Warnings

  • • Serious hypersensitivity; Clostridioides difficile-associated diarrhoea; seizures (especially with renal impairment). FDA Meropenem · 5

Important interactions

  • • Valproic acid: marked fall in valproate levels and breakthrough seizures — not recommended together. FDA Meropenem · 5

Renal adjustment

  • • eGFR < 50: CrCl 26–50: usual dose every 12 h; 10–25: half dose every 12 h; <10: half dose every 24 h. FDA Meropenem · 2.2

Formulations

👥 Special populations

  • 🤰 PregnancyUse with caution

    Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Meropenem · 8.1

    “Risk Summary There are insufficient human data to establish whether there is a drug-associated risk of major birth defects or miscarriages with meropenem in pregnant women.”
  • 🤱 BreastfeedingUse with caution

    Label: use with caution while breastfeeding; see the label text. FDA Meropenem · 8.2

    “Risk Summary Meropenem has been reported to be excreted in human milk.”
  • 👶 ChildrenUse with caution

    The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Meropenem · 8.4

    “The safety and effectiveness of Meropenem for injection have been established for pediatric patients 3 months of age and older with complicated skin and skin structure infections and bacterial meningitis, and for pediatric patients of all ages with complicated intra-abdominal infections.”
  • 👴 Older adultsUse with caution

    Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Meropenem · 8.5

    “Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function.”
  • ⚥ Females & males of reproductive potentialNo data

    The source for this drug has no section for this group.

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