Imipenem-cilastatin

🧮 Dose calculator

Sepsis / serious hospital infection (refer) · Regimen source: FDA Primaxin · 2.1

• • Less susceptible organisms: 1 g every 6 h. Dose refers to imipenem. FDA Primaxin · 2.1

Enter age (weight is optional for this regimen).

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Primaxin · 8.1

  “Risk Summary Available data from a small number of postmarketing cases with PRIMAXIN use in pregnancy are not sufficient to identify any drug-associated risks for major birth defects, miscarriage, or adverse maternal or fetal outcomes.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Primaxin · 8.2

  “Risk Summary There are insufficient data on the presence of imipenem/cilastatin in human milk, and no data on the effects on the breastfed child, or the effects on milk production.”

• 👶 ChildrenSafety not established

  Label: safety and effectiveness in children have not been established. FDA Primaxin · 8.4

  “PRIMAXIN is not recommended in pediatric patients with CNS infections because of the risk of seizures.”

• 👴 Older adultsUse with caution

  Label: use with caution in older adults, usually starting at the low end of the dose range. FDA Primaxin · 8.5

  “Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function.”

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.