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Clarithromycin

کلاریترومایسین

⚠ Unverified

💊 AntibioticsMacrolide

Market / country: 🇺🇸 USA

Biaxin (US)

🧮 Dose calculator

Disease / regimen

Streptococcal pharyngitis / tonsillitis · Regimen source: FDA Clarithromycin susp · 2.4 FDA Clarithromycin susp · 8.4

Formulation

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🛡️ Safety & information

Contraindications

⛔ Hypersensitivity to clarithromycin, erythromycin or any macrolide. FDA Clarithromycin susp · 4.1
⛔ Concomitant cisapride or pimozide (fatal arrhythmias). FDA Clarithromycin susp · 4.2
⛔ History of cholestatic jaundice/hepatic dysfunction with clarithromycin. FDA Clarithromycin susp · 4.3
⛔ With colchicine in renal or hepatic impairment. FDA Clarithromycin susp · 4.4
⛔ With lomitapide, lovastatin or simvastatin. FDA Clarithromycin susp · 4.5
⛔ Safety and effectiveness established only from 6 months. FDA Clarithromycin susp · 8.4

Warnings

• Severe acute hypersensitivity reactions FDA Clarithromycin susp · 5.1
• QT prolongation FDA Clarithromycin susp · 5.2
• Hepatotoxicity FDA Clarithromycin susp · 5.3
• Serious adverse reactions with concomitant drugs FDA Clarithromycin susp · 5.4
• Clostridium difficile-associated diarrhea FDA Clarithromycin susp · 5.6
• Exacerbation of myasthenia gravis FDA Clarithromycin susp · 5.8

Renal adjustment

• eGFR < 30: CrCl <30 mL/min: reduce dose by 50%. FDA Clarithromycin susp · 2.6

Formulations

125 mg / 5 mL — suspension 🇺🇸 USA FDA Clarithromycin susp · 3
250 mg / 5 mL — suspension 🇺🇸 USA FDA Clarithromycin susp · 3

📚 Reference status for this drug

Shows which sources have references recorded for this drug and which do not.

FDA label (DailyMed)✅ Present
FDA Clarithromycin susp · 3 FDA Clarithromycin susp · 2.4 FDA Clarithromycin susp · 8.4 FDA Clarithromycin tab · 2.2, Table 1 FDA Clarithromycin susp · 1.6 FDA Clarithromycin susp · 4.1 FDA Clarithromycin susp · 4.2 FDA Clarithromycin susp · 4.3 FDA Clarithromycin susp · 4.4 FDA Clarithromycin susp · 4.5 FDA Clarithromycin susp · 5.1 FDA Clarithromycin susp · 5.2 FDA Clarithromycin susp · 5.3 FDA Clarithromycin susp · 5.4 FDA Clarithromycin susp · 5.6 FDA Clarithromycin susp · 5.8 FDA Clarithromycin susp · 2.6
UK SmPC (eMC / MHRA)❌ Not present
Published guideline❌ Not present
Licensed reference (medical school)❌ Not present
Iranian leaflet (IFDA)❌ Not present
Clinical review⚠ Unverified

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