Ampicillin + sulbactam (injection)
آمپیسیلین + سولباکتام (تزریقی)
🦠 Antiinfectives For Systemic UsePenicillin + beta-lactamase inhibitor
Market / country: 🇺🇸 USA
Unasyn (US)
🧮 Dose calculator
Skin and skin structure infection · Regimen source: FDA Ampicillin-sulbactam · Dosage and Administration
- • Sulbactam max 4 g/day (= 12 g combined). FDA Ampicillin-sulbactam · Dosage and Administration
Enter age (weight is optional for this regimen).
🛡️ Safety & information
Contraindications
- ⛔ Serious beta-lactam hypersensitivity; prior cholestatic jaundice with this drug. FDA Ampicillin-sulbactam · Contraindications
Formulations
- 1.5 g vial (ampicillin 1 g + sulbactam 0.5 g) — powder for injection 🇺🇸 USA FDA Ampicillin-sulbactam · How Supplied
- 3 g vial (ampicillin 2 g + sulbactam 1 g) — powder for injection 🇺🇸 USA FDA Ampicillin-sulbactam · How Supplied
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Ampicillin-sulbactam · Pregnancy
“Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed (see PRECAUTIONS-Drug/Laboratory Test Interactions section).”
- 🤱 BreastfeedingUse with caution
Label: use with caution while breastfeeding; see the label text. FDA Ampicillin-sulbactam · Nursing Mothers
“Low concentrations of ampicillin and sulbactam are excreted in the milk; therefore, caution should be exercised when Ampicillin and Sulbactam for Injection is administered to a nursing woman.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Ampicillin-sulbactam · Pediatric Use
“The safety and effectiveness of Ampicillin and Sulbactam for Injection have been established for pediatric patients one year of age and older for skin and skin structure infections as approved in adults.”
- 👴 Older adultsNo data
The source for this drug has no section for this group.
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)ANDA201406
- DailyMed (FDA label)FDA Ampicillin-sulbactam
- MedlinePlus (NIH)AmpicillinAmpicillin Injection
- WHO ATC/DDDJ01CR01
- Darooyab (Iran)Ampicillin-Sulbactam
🇮🇷 Registered in Iran Darooyab · G-4599/Ampicillin-Sulbactam
Dosage forms with Iranian generic codes, per Darooyab.
- 06939 · AMPICILLIN/SULBACTAM 1G/0.5G VIAL · ویال آمپیسیلین / سولباکتام ۱ گرم / ۰٫۵ گرم
- 06938 · AMPICILLIN/SULBACTAM 2G/1G VIAL · ویال آمپیسیلین / سولباکتام ۲ گرم / ۱ گرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Ampicillin-sulbactam · How SuppliedFDA Ampicillin-sulbactam · Dosage and AdministrationFDA Ampicillin-sulbactam · ContraindicationsFDA Ampicillin-sulbactam · SPL approval / marketing categoryFDA Ampicillin-sulbactam · PregnancyFDA Ampicillin-sulbactam · Nursing MothersFDA Ampicillin-sulbactam · Pediatric Use
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-4599/Ampicillin-Sulbactam
- Clinical review⚠ Unverified