Flucytosine
فلوسیتوزین
🦠 Antiinfectives For Systemic UseAntifungal (antimetabolite)
Market / country: 🇺🇸 USA
Ancobon (US)
🧮 Dose calculator
Invasive fungal infection (aspergillosis, candidaemia, cryptococcosis) — hospital · Regimen source: FDA Flucytosine · Dosage and Administration
- • Give capsules a few at a time over 15 min (less nausea). Renal impairment: lower dose and monitor levels. Resistance develops when used alone. FDA Flucytosine · Dosage and AdministrationFDA Flucytosine · Warnings
Enter age and weight.
🛡️ Safety & information
Contraindications
- ⛔ Hypersensitivity to flucytosine. FDA Flucytosine · Contraindications
Warnings
- • Boxed warning: extreme caution in renal impairment; bone-marrow suppression; monitor haematology, renal and hepatic function. FDA Flucytosine · Warnings
Formulations
- 250 mg capsule — capsule 🇺🇸 USA FDA Flucytosine · How Supplied
- 500 mg capsule — capsule 🇺🇸 USA FDA Flucytosine · How Supplied
👥 Special populations
- 🤰 PregnancyUse with caution
Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Flucytosine · Pregnancy
“Flucytosine Capsules USP should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.”
- 🤱 BreastfeedingDangerous / avoid
Label: breastfeeding not recommended, or choose between the drug and breastfeeding. FDA Flucytosine · Nursing Mothers
“Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants from Flucytosine Capsules USP, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.”
- 👶 ChildrenUse with caution
The label has conditions, age limits or notes for children; the label sentence is quoted below. FDA Flucytosine · Pediatric Use
“The efficacy and safety of Flucytosine Capsules USP have not been systematically studied in pediatric patients.”
- 👴 Older adultsNo data
The source for this drug has no section for this group.
- ⚥ Females & males of reproductive potentialNo data
The source for this drug has no section for this group.
🔗 Reference links
- FDA (approval record)ANDA204652
- DailyMed (FDA label)FDA Flucytosine
- MedlinePlus (NIH)❌ None
- WHO ATC/DDDJ02AX01
- Darooyab (Iran)Flucytosine
🇮🇷 Registered in Iran Darooyab · G-718/Flucytosine
Dosage forms with Iranian generic codes, per Darooyab.
- 00541 · FLUCYTOSINE 500MG TAB · قرص فلوسیتوسین ۵۰۰ میلیگرم
📚 Reference status for this drug
Shows which sources have references recorded for this drug and which do not.
- FDA label (DailyMed)✅ PresentFDA Flucytosine · How SuppliedFDA Flucytosine · Dosage and AdministrationFDA Flucytosine · WarningsFDA Flucytosine · ContraindicationsFDA Flucytosine · SPL approval / marketing categoryFDA Flucytosine · PregnancyFDA Flucytosine · Nursing MothersFDA Flucytosine · Pediatric Use
- UK SmPC (eMC / MHRA)❌ Not present
- Published guideline❌ Not present
- Licensed reference (medical school)❌ Not present
- Iranian leaflet (IFDA)❌ Not present
- Pharmacy website (secondary, unreliable)✅ PresentDarooyab · G-718/Flucytosine
- Clinical review⚠ Unverified