Amphotericin B (conventional deoxycholate)

🧮 Dose calculator

Mucormycosis · Regimen source: FDA Amphotericin B · Dosage and Administration

• • Only for progressive, life-threatening fungal infection. Test dose 1 mg over 20–30 min. Start 0.25 mg/kg/day (0.3 if severe and rapidly progressive), increase gradually to 0.5–0.7 mg/kg/day; max 1 mg/kg daily or 1.5 mg/kg on alternate days. Infuse over 2–6 h at 0.1 mg/mL. FDA Amphotericin B · Dosage and Administration
• • Rhinocerebral mucormycosis generally occurs with diabetic ketoacidosis; restoring diabetic control is imperative for treatment to succeed. FDA Amphotericin B · Dosage and Administration

Enter age and weight.

👥 Special populations

• 🤰 PregnancyUse with caution

  Label states no clear risk or has limited data; use only if needed, under medical advice. FDA Amphotericin B · Pregnancy

  “Teratogenic Effects Pregnancy Category B : Reproduction studies in animals have revealed no evidence of harm to the fetus due to amphotericin B for injection.”

• 🤱 BreastfeedingUse with caution

  Label: use with caution while breastfeeding; see the label text. FDA Amphotericin B · Nursing Mothers

  “Because many drugs are excreted in human milk and considering the potential toxicity of amphotericin B, it is prudent to advise a nursing mother to discontinue nursing.”

• 👶 ChildrenSafety not established

  Label: safety and effectiveness in children have not been established. FDA Amphotericin B · Pediatric Use

  “Safety and effectiveness in pediatric patients have not been established through adequate and well-controlled studies.”

• 👴 Older adultsNo data

  The source for this drug has no section for this group.

• ⚥ Females & males of reproductive potentialNo data

  The source for this drug has no section for this group.